"Think ahead. Don't let day-to-day operations drive out your planning." - Donald Rumsfeld or Spend time working ON your business not just IN it.
Have you written down your goals for 2009? How about for 2012? Who is keeping you accountable?"
Build as many systems as you can. (Policies and procedures too; that's what a wiki is for).
Layne mentioned Culture. Jack Daly says that Culture is THE most important part of building your business.
Pareto's Principle is every where. Don't let one issue or person hog all of your (mental) bandwidth.
Also, learn to delegate. (I need to do more of that and those systems things.)
Do you have a mental spam filter? Silly Pointless And Meaningless = SPAM.
Don't use Substandard Components. It's all about Talent.
Reporting: so you can baseline your business and know where the problems are. Make an appointment in your schedule to review reports. (Also, to make a couple of cold calls! :)
Get an outside perspective on your business.
Build redundancy into everything, including Knowledge. When you lose key people, you lose huge amounts of knowledge.